Although the word translated as a group originally meant something like “with one mind” or “of one accord,” it seems quite likely that by New Testament times it had become weakened to mean simply “together.”
Frequently precedes the verb phrase to pray in order to bring out the meaning of the Greek verbal construction which emphasizes that the praying was done either continuously or frequently. A similar emphasis is also brought out by the Jerusalem Bible, “these joined in continuous prayer,” and by the New English Bible, “these were constantly at prayer together.” But it seems preferable to translate “frequent” rather than “constant” or “continuous.”
It is difficult to define precisely the relationship between Mary the mother of Jesus and the women spoken of, though it is very unlikely that the women should be understood as the wives of the men involved. Perhaps Mary was included within the group of the women, but because of her unique relationship to the Lord she was given specific mention; and in any case Luke elsewhere, as in the nativity narratives, lets his high regard for Mary be known.
The fact that the participants who joined together in prayer are syntactically divided between they and the postponed series the women, and with Mary … and his brothers makes for a very awkward statement in many languages. Accordingly, the arrangement is often recast, for example, “the apostles, together with the women, and Mary the mother of Jesus, and his brothers, joined together in a group to pray frequently.”
Quoted with permission from Newman, Barclay M. and Nida, Eugene A. A Handbook on The Acts of the Apostles. (UBS Handbook Series). New York: UBS, 1972. For this and other handbooks for translators see here .

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