Exegesis:
eperōtō humas, ei exestin ‘I ask you whether it is permitted.’ For eperōtō cf. on 2.46; for exestin on v. 2.
agathopoiēsai ē kakopoiēsai ‘to do good or to do harm.’
agathopoieō ‘to do good,’ in the sense of helping.
kakopoieō ‘to do wrong’ or ‘to harm,’ here probably in the latter meaning.
psuchēn sōsai ē apolesai ‘to save life or to destroy (it),’ an explanation of what agathopoiēsai ē kakopoiēsai refer to. psuchē (cf. on 1.46) means here ‘human life’ nor ‘living person.’ apollumi means ‘to destroy,’ rather than “to let perish” (Twentieth Century New Testament, cf. also Nieuwe Vertaling and Willibrord).
Translation:
Said to them. A specification of the pronoun may be necessary, e.g. ‘to the men who were watching’ (Javanese).
I ask you helps to bring out the decisive character of the subsequent question, hence ‘I put this question to you’ (cf. New English Bible, Balinese).
Is it lawful on the sabbath to do good or to do harm…?, a question anticipating the answer: only to do good (is lawful on the sabbath). Idiom may require finite verbal forms, e.g. ‘that we do good or do harm’ (cf. Tzeltal, Tboli). A question, asking for a choice between two (or more) alternatives may require a specific connective, e.g. ‘or-else’ (lit. if not so) (Sranan Tongo), or an interrogative pronoun meaning ‘which-one-out-of-two (or more)’ (Javanese). To do good or to do harm, or, ‘to do what is good or to do what is harmful/bad’ (Tae,’ Batak Toba). It may be necessary to add an object, ‘to do a person good or to do him harm.’
To save life, or, ‘to save a person,’ ‘to save a person’s life.’ The verb is used here in the sense of ‘to deliver from bodily harm.’ Some renderings used here are, ‘to spare (lit. hide) a person’s life’ (Sranan Tongo), ‘to snatch away life from danger’ (Cuyono).
To destroy it, or, ‘to destroy/kill him, or, that person.’
Quoted with permission from Reiling, J. and Swellengrebel, J.L. A Handbook on the Gospel of Luke. (UBS Handbook Series). New York: UBS, 1971. For this and other handbooks for translators see here . Make sure to also consult the Handbook on the Gospel of Mark for parallel or similar verses.

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