Exegesis:
humeis este hoi dikaiountes heautous ‘you are the people who justify yourselves,’ i.e. ‘you are characterized by the fact that you justify yourselves.’ dikaioō means here ‘to claim to be just,’ ‘to present as just.’
enōpion tōn anthrōpōn ‘in the sight of men,’ going with hoi dikaiountes heautous.
ho de theos ginōskei tas kardias humōn ‘but God knows your hearts,’ contrasting with enōpion tōn anthrōpōn.
hoti to en anthrōpois hupsēlon lit. ‘for that which is high among men,’ in the present context, ‘that which is highly regarded among men without foundation.’
hupsēlos ‘high,’ here figuratively, ‘highly regarded,’ ‘esteemed.’
bdelugma enōpion tou theou ‘(is) an abomination in the sight of God,’ with estin understood.
bdelugma ‘abomination,’ ‘detestable thing.’
Translation:
Justify yourselves before men, or, ‘pose as just/righteous (cf. on 1.6) before men,’ ‘give yourselves the appearance of straight hearts’ (Kekchi), ‘want people to regard you as (take you to be) righteous,’ cf. “like the world to look at you and say, ‘What upright men!’ ” (The Four Gospels – a New Translation).
Knows your hearts, or, ‘your mind/inward-being/thoughts’; or, ‘knows who you (really) are,’ cf. “sees through you” (New English Bible).
What is exalted among men, or, ‘what people regard as exalted’ (cf. on 1.52).
Is an abomination in the sight of God, or, ‘is detested by God’ (Tae’), ‘brings-disgust-in God’s heart’ (Balinese), ‘God regards as filthy things’ (Sranan Tongo).
Quoted with permission from Reiling, J. and Swellengrebel, J.L. A Handbook on the Gospel of Luke. (UBS Handbook Series). New York: UBS, 1971. For this and other handbooks for translators see here . Make sure to also consult the Handbook on the Gospel of Mark for parallel or similar verses.

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