Exegesis:

kai epērōtēsan auton ‘and they asked him.’ The question they ask does not come until v. 22; it is preceded by a flattering statement concerning Jesus.

didaskale ‘teacher,’ cf. on 3.12.

oidamen hoti orthōs legeis kai didaskeis ‘we know that you speak and teach correctly.’ orthōs may refer to the manner of Jesus’ speaking and teaching, ‘forthrightly’ (cf. Willibrord), or to the content of his speaking and teaching. The latter is preferable.

ou lambaneis prosōpon lit. ‘you do not accept a person,’ a very strong Hebraism quite frequent in the Septuagint. It means ‘to show partiality,’ ‘to show favouritism.’

ep’ alētheias ‘truly,’ cf. on 4.25.

tēn hodon tou theou didaskeis lit. ‘you teach the way of God.’

Translation:

They asked him The verb ‘to ask’ is in some cases better avoided, because a question does not follow directly; cf. ‘they told him’ (Kituba), “these spies said to Jesus” (Good News Translation, which introduces v. 22 by “tell us”).

Rightly, preferably, ‘what is right,’ cf. “what you … teach is right” (Good News Translation).

You … show no partiality, or, ‘you do-not choose-choose people’ (Trukese), ‘there exists no preference of one over another with you’ (Zarma), ‘you do not make-difference-between people’ (Toraja-Sa’dan), ‘you do not observe hairs-on-the-body’ (Bahasa Indonesia RC, using an idiom for discrimination).

Truly refers to the truth of his teaching; hence ‘in a true way,’ ‘with true words.’

The way of God, or, ‘the commandments/instructions of God’ (Balinese).

Quoted with permission from Reiling, J. and Swellengrebel, J.L. A Handbook on the Gospel of Luke. (UBS Handbook Series). New York: UBS, 1971. For this and other handbooks for translators see here . Make sure to also consult the Handbook on the Gospel of Mark for parallel or similar verses.