It shall be the most lowly of the kingdoms means Egypt will be “the weakest kingdom of all” (Good News Translation; similarly New Century Version). For lowly see the previous verse.

And never again exalt itself above the nations means Egypt will not become powerful again. This clause may be rendered “and it will never again consider itself more powerful [or, important] than the other nations” or “and it will never again rule other nations” (New Century Version; similarly Good News Translation).

And I will make them so small that they will never again rule over the nations: God will make sure that Egypt will never become powerful again by making the Egyptians so weak politically that they will never control other nations again. In this context the Hebrew word for small does not mean physically little, but “[politically] weak” (New International Version, New International Reader’s Version, New Century Version) or “unimportant” (Good News Translation). But the fact that the Hebrew, followed by Revised Standard Version, changes from the singular pronouns It/itself (that is, Egypt) to the plural pronouns them/they (that is, the Egyptians) in this verse suggests that a better rendering for small may be “few [in number]” (Revised English Bible, New American Bible). Either interpretation is acceptable. One model for this sentence is “I will make them so unimportant that they will never again rule over other nations.”

Quoted with permission from Gross, Carl & Stine, Philip C. A Handbook on Ezekiel. (UBS Helps for Translators). Miami: UBS, 2016. For this and other handbooks for translators see here .