Good News Translation‘s paragraph break here is appropriate since there is a slight change in the subject matter.

The Lord created medicines from the earth: This refers to plants that are used for medicinal purposes, but that grow in the soil, and it would be good to make this clear. New Jerusalem Bible says “The Lord has brought forth medicinal herbs from the ground.”

And a sensible man will not despise them: People would not despise medicine in the sense that they might despise a person. Good News Translation expresses the meaning here well with “and a sensible person will not hesitate to use them,” or we may say “and if you are sensible, you will use them.”

Quoted with permission from Bullard, Roger A. and Hatton, Howard A. A Handbook on Sirach. (UBS Helps for Translators). New York: UBS, 2008. For this and other handbooks for translators see here.