they will pick up snakes (in their hands)

The Greek that is translated as “they will pick up snakes (in their hands)” or similar in English is translated in Southern Puebla Mixtec as “if by chance they pick up any poisonous snake” and in Palantla Chinantec as “if they should take hold of a snake accidentally.” (Source: B. Moore / G. Turner in Notes on Translation 1967, p. 1ff.)

See also complete verse (Mark 16:18).