The Greek that is translated as something like “worried (or: anxious) and bothered about many things” is translated in Tzeltal as “doing all kinds of things has gone to your heart and you have difficulty because of it.”
In the German New Testament translation by Berger / Nord (publ. 1999) it is translated idiomatically as ich will dir anerkennen, dass du vor lauter Machen und Tun nicht weiß, wo dir der Kopf steht or “I will acknowledge that you don’t know where your head is because of all the doing and making.”
The term that is translated as “worried (or anxious)” in English is often translated idiomatically. Examples include “eating for oneself one’s heart” (Shona, version of 1966), “black with worry” (Chichewa), “breaking one’s head” (Sranan-Tongo), “hanging up the heart” (Bulu), “crumbling in one’s abdomen” (Western Kanjobal), “one’s stomach is rising up” (Farefare), or “one’s mind is killing one” (Navajo).
See also troubled / perplexed and worry and see also Seat of the Mind for traditional views of “ways of knowing, thinking, and feeling.”